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Octreotide 5mg
$120.00
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Product is injectable, in powder form, needs reconstitution before use. Please read more on our FAQ page
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Octreotide, a synthetic octapeptide developed by chemist Wilfried Bauer in 1979, powerfully inhibits growth hormone, glucagon, and insulin, surpassing the natural hormone somatostatin. It primarily binds to somatostatin receptors SSTR2 and SSTR5. Octreotide treats various conditions, including acromegaly, gigantism from growth hormone tumors, thyrotropinoma-linked pituitary tumors, carcinoid syndrome-induced diarrhea and flushing, vasoactive intestinal peptide tumor-associated diarrhea, and mild glucagonoma cases unsuitable for surgery.
DISCLAIMER:
This PRODUCT IS INTENDED FOR RESEARCH PURPOSES ONLY. Its usage should be limited to in vitro testing and laboratory experimentation. This product is not intended for any other purposes, including but not limited to medical, therapeutic, or diagnostic applications. It must not be used on humans, animals, or any living organisms.
Only licensed and qualified professionals with appropriate expertise should handle and manipulate this product. Any unauthorized use or misuse of this product is strictly prohibited by law. The manufacturer, distributor, and seller of this product do not assume any responsibility for its misuse or any consequences resulting from such behavior. By accessing or using this product, you agree to abide by these terms and conditions and acknowledge the inherent risks associated with its usage.
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Description
What is Octreotide?
Octreotide, an octapeptide, pharmacologically mimics natural somatostatin but exerts stronger inhibition on growth hormone, glucagon, and insulin compared to the natural hormone. This synthetic compound, initially created by chemist Wilfried Bauer in 1979, primarily binds to somatostatin receptors SSTR2 and SSTR5.
Octreotide is employed in the management of various conditions, including acromegaly and gigantism resulting from growth hormone-producing tumors, pituitary tumors that release thyroid-stimulating hormone (thyrotropinomata), diarrhea and flushing episodes linked to carcinoid syndrome, and diarrhea in individuals with vasoactive intestinal peptide-secreting tumors (VIPomas). Additionally, it finds use in mild glucagonoma cases when surgery is not a viable option.
Medical Application.
Octreotide is employed in the management of various conditions, including acromegaly and gigantism resulting from growth hormone-producing tumors, pituitary tumors that release thyroid-stimulating hormone (thyrotropinomata), diarrhea and flushing episodes linked to carcinoid syndrome, and diarrhea in individuals with vasoactive intestinal peptide-secreting tumors (VIPomas). Additionally, it finds use in mild glucagonoma cases when surgery is not a viable option.
Octreotide is frequently administered through an infusion to address acute bleeding from esophageal varices in liver cirrhosis. This is done with the expectation that it can lower portal venous pressure. However, current evidence indicates that this pressure reduction is short-lived and does not enhance overall survival.
Octreotide is also applicable in the treatment of acromegaly, a condition characterized by excessive growth hormone (GH) production. Functioning as a somatostatin analog, octreotide hinders GH release from the pituitary gland by engaging in a feedback mechanism.
Octreotide assists in handling fistulas by decreasing gastrointestinal secretions and slowing down gastrointestinal movement, thereby regulating and decreasing their output. However, its effectiveness in healing intestinal fistulas remains unconfirmed, and its regular use is restricted due to associated side effects.
Octreotide is additionally employed to address challenging cases of hypoglycemia in neonates with congenital hyperinsulinism and in adults experiencing sulphonylurea-induced hypoglycemia.
It proves beneficial in managing overdoses of sulfonylurea-type antidiabetic medications, particularly when these cases recur or do not respond well to intravenous dextrose. Octreotide operates by suppressing insulin secretion.
Possible side effects.
Studies have documented side effects including diarrhea, bloating, gas, and abdominal pain. It’s challenging to determine whether these effects are linked to the medication or the underlying condition. Administering injections between meals or before bedtime may reduce these side effects. Additional potential side effects encompass nausea, vomiting, and alterations in blood sugar levels.
Additional info
| Weight | 4 g |
|---|---|
| Dimensions | 10 × 10 × 20 mm |
| Weight | 5mg, 10mg |
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