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Selank, a synthetic peptide that mimics tuftsin, offers a range of therapeutic benefits. Notably, it has been found to possess potent anti-anxiety properties, helping individuals find relief from stress and anxiety. Moreover, Selank has shown promising effects in enhancing memory and improving learning capabilities. Researchers have also explored its impact on pain perception, suggesting that Selank may have potential as a therapeutic option for managing pain. With its diverse range of positive effects, Selank continues to be an intriguing subject for further exploration in the field of neuroscience and mental health.
This PRODUCT IS INTENDED FOR RESEARCH PURPOSES ONLY. Its usage should be limited to in vitro testing and laboratory experimentation. This product is not intended for any other purposes, including but not limited to medical, therapeutic, or diagnostic applications. It must not be used on humans, animals, or any living organisms.
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Selank is a synthetic peptide that was developed in Russia as a potential treatment for anxiety and cognitive disorders. It is derived from the naturally occurring peptide tuftsin, which modulates the immune response.
Selank is primarily used for its anxiolytic (anti-anxiety) properties. It has been found to reduce anxiety and promote a sense of calmness and relaxation. It works by regulating the release of stress hormones in the body, such as cortisol, and modulating the activity of neurotransmitters like serotonin and dopamine.
In addition to its anxiolytic effects, Selank has also shown potential as a cognitive enhancer. It may improve memory, focus, and mental clarity, making it useful for individuals looking to optimize their cognitive performance. Research suggests that Selank increases dopamine and serotonin levels in the brain, which are involved in various cognitive processes.
Selank has also been studied for its immunomodulatory properties. It can help regulate and balance the immune system response; potentially benefiting conditions associated with immune dysfunction. However, more research is needed to fully understand its efficacy.
- Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
- Molecular Formula: C33H57N11O9
- Molecular Weight: 751.887 g/mol
- PubChem CID: 11765600
- CAS Number: 129954-34-3
- Synonyms: Selanc
Selank Anxiety Effects Based on Genes Related to GABA Neurotransmitter
According to a study published in the National Center for Biotechnology Information (NCBI), the administration of Selank has been found to affect the mRNA levels of genes involved in neurotransmission, specifically those related to the GABA neurotransmitter, in the frontal cortex of rats. This suggests that Selank may have an impact on the GABAergic system, which is involved in anxiety regulation.
Another study published on NCBI states that Selank has an anxiolytic effect comparable to classical benzodiazepine drugs, which enhance the function of the GABA neurotransmitter. This further supports the notion that Selank affects the GABAergic system and can help reduce anxiety.
Changes in gene expression as a function of time in rats treated with Selank.
Additionally, research indicates that Selank might influence the expression of certain genes involved in GABAergic neurotransmission. This effect on gene expression may contribute to Selank’s anxiolytic properties.
Selank and the Immune System in Anxiety
Selank, a synthetic peptide, has been studied for its potential effects on the immune system in anxiety. The connection between Selank and the immune system lies in its immunomodulatory properties. Research suggests that Selank can serve as a novel immunomodulator in patients that suffer from anxiety-asthenic disorders by regulating cytokine levels. Cytokines are small proteins involved in cell signaling and immune responses.
Inflammatory processes and immune responses play a role in anxiety disorders, and Selank has shown potential in modulating these factors. Studies indicate that Selank can influence cytokine levels under conditions of social stress, suggesting its impact on the immune system. This implies that Selank may help regulate immune responses associated with anxiety.
Furthermore, Selank has been associated with antiviral immune-stimulatory effects, potentially strengthening and stimulating immune function. By enhancing immune function, Selank may contribute to an overall improvement in anxiety symptoms.
While the exact mechanisms through which Selank affects the immune system in anxiety are still being investigated, these studies suggest a connection between Selank, immune modulation, and anxiety.
Selank Research with Memory and Learning
Selank is a synthetic peptide studied for its effects on memory and learning processes. Several research studies have investigated the impact of Selank on cognitive function and have found positive results.
One study published in the journal “Bulletin of Experimental Biology and Medicine” showed that Selank protected against ethanol-induced memory impairment by regulating the content of brain-derived neurotrophic factor (BDNF) in the hippocampus and prefrontal cortex. BDNF is a protein that plays a crucial role in promoting the survival and growth of neurons, as well as in synaptic plasticity, which is essential for learning and memory formation.
Another study conducted on rats examined the actions of Selank on learning and memory processes using an active avoidance conditioned reflex. The researchers found that Selank had optimized actions on memory and improved the learning process.
Furthermore, research published in the journal “Neuroscience and Behavioral Physiology” demonstrated that Selank facilitated learning in animals exposed to hypoxia, a condition of low oxygen levels. The study suggested that Selank could correct cognitive impairments resulting from antenatal hypoxia.
Additionally, a study conducted on rats in unpredictable chronic mild stress conditions found that Selank enhanced the effect of diazepam, a benzodiazepine drug, in reducing anxiety. This suggests that Selank may have potential anxiolytic properties that positively impact cognitive function.
Selank Research and Pain
Selank seems to play a role in preventing the breakdown of natural enkephalins, which are peptides that bind to opioid receptors and help reduce the severity of pain. Enkephalins are also involved in the body’s stress response and are found abundantly in the brain and adrenal glands. By preserving the levels of enkephalins in the brain, Selank may help reduce the impact of stress on memory, learning, and concentration.
Importantly, Selank has been found to have minimal side effects and is well-absorbed when administered subcutaneously in mice. However, it’s important to note that the dosage used in mice does not directly translate to humans. The Selank available for purchase at our shop is intended solely for educational and scientific research purposes, and it is not meant for human consumption. Only individuals with a valid research license should consider acquiring it.
Please note that all the articles and product information provided on this website are intended for informational and educational purposes only.
The products offered on this platform are specifically designed for in-vitro studies, meaning they are conducted outside the body. It is important to clarify that these products are not medicines or drugs, and the FDA has not approved them for the prevention, treatment, or cure of any medical condition, ailment, or disease.
The above literature was researched, edited and organized by Dr. Logan, M.D. Dr. Logan holds a doctorate degree from Case Western Reserve University School of Medicine and a B.S. in molecular biology.
Scientific Journal Author
Dr. Petr Slominsky‘s 169 research works with 803 citations. 12 of those papers pertain to the examination of Selank’s diverse, multifaceted effects e.g. anxiety reduction, changes in the transcription profile of the hippocampus, and changes in expression of the genes for chemokines, cytokines, and their receptors. Dr. Slominsky is particularly interested in the epigenetic effects of it and other disease-state pathologies.
Dr. Petr Slominsky is being referenced as one of the leading scientists involved in the research and development of Selank. In no way is this doctor/scientist endorsing or advocating the purchase, sale, or use of this product for any reason. There is no affiliation or relationship, implied or otherwise, between Peptide Shop and this doctor. The purpose of citing the doctor is to acknowledge, recognize, and credit the exhaustive research and development efforts conducted by the scientists studying this peptide.
ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.
|Dimensions||10 × 10 × 20 mm|