Just like GHRP-2, GHRP-6 is a potent growth hormone secretion secretagogue as it promotes GH release from the anterior pituitary gland. It also acts as a ghrelin receptor agonist. Ghrelin is an important gut hormone which activates growth hormone secretion, regulates food intake and fat deposition.
GHRP-6 was first initially described in 1994 when it was found it was the first member of its family that has such a profound effect on GH secretion. Given this effect, along with ghrelin activation, GHRP-6 was of significant scientific interest with huge future research potential.
References:
- https://www.researchgate.net/publication/235256728_Pharmacokinetic_study_of_Growth_Hormone-Releasing_Peptide_6_GHRP-6_in_nine_male_healthy_volunteers
- https://pubmed.ncbi.nlm.nih.gov/23099431/
- https://pubmed.ncbi.nlm.nih.gov/21298258/
- https://www.sciencedirect.com/science/article/abs/pii/0024320596003566