LL-37 is an antimicrobial peptide that’s generated by the epithelial cells, neutrophils and lymphocytes, which is one of the essential cogs in the antiviral, antifungal and antibacterial defense mechanism.
LL-37’s mechanism of action is not too dissimilar to that of other antimicrobial peptides, it damages/punctures harmful microorganism’s (fungal, bacterial, viral pathogen’s) cell membrane. This is how LL-37 inhibits the creation of bacterial biofilms which, in turn, reduces the incidence of chronic and recurrent microbial infections.
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