Teriparatide is a derivative of human parathyroid hormone (PTH) which consists of its first biologically active amino(N)-terminal 34 amino acids.
Endogenous PTH is one of the primary regulators of calcium and phosphate metabolism within the body, it has the potential to increase calcium, resulting in increased bone resorption. Since changes in PTH and its variation affect bone density and depletion, there is more and more research around teriparatide to see if it has the potential to affect this bone resorption process.