We live in an age where peptides are valuable resources that seem to affect well-being and quality of life to a great extent. Since peptides gained popularity, Tesamorelin and Sermorelin have become almost inseparable components of the fitness and medical industry, and they are being researched for the benefits they could bring to both fields alike.
Their potential impact on general well-being is normally connected to reshaping the body, redistributing body mass, the process of aging, and improving cognitive functions – practically many of the crucial factors for a good quality of life in general. But how do they work their magic?
Similar in structure, these synthetic peptides are made to stimulate the release of growth hormone (GH) from the pituitary gland. How can that impact health and well-being? In this review, let us get inside-out knowledge of their benefits, differences, and dosage of these peptides.
What is Tesamorelin?
This powerful peptide is a synthetic version of a growth hormone-releasing hormone (GHRH), a naturally occurring hormone in the body that stimulates the release of growth hormone (GH) from the pituitary gland. In other words, the Tesamorelin peptide can greatly influence and reduce excess abdominal fat.
It first appeared and it was approved as a prescription medication in the field of medicine. Notably, ever since, Tesamorelin has greatly benefited people living with HIV/AIDS who have developed lipodystrophy. Lipodystrophy is a condition, characterized by abnormal fat distribution in the body. It affects abdominal internal organs as the fat gets stored more around that area, while gaining weight, rather than being evenly distributed all over the body.
Luckily, the researchers have found that Tesamorelin stimulates the pituitary gland to release growth hormone, and reduces the fat stored in the abdominal area improving body composition in these individuals. This is how it all started.
Sermorelin
Talking about Sermorelin peptide, it is an older, better-researched, and shorter synthetic peptide than Tesamorelin. This version of the growth hormone-releasing hormone (GHRH) is necessary for growth in children and adults.
Similarly to Tesamorelin, its success started in the medical field after it was discovered that it provides a natural way of supporting the growth hormone release in the body. This contributed to its immediate usage in treating children with growth hormone deficiency. It never replaced growth hormone (GH); rather, it stimulated the pituitary gland to release it, thus increasing GH levels. Regardless of its immediate success, its manufacturer discontinued its production due to the lack of commercial potential, and Semorelin was taken off the FDA-approved peptide list.
Nevertheless, it never stopped attracting attention and research studies, as the benefits of natural stimulation of growth hormones have been reported to be helpful in more than one way, from relieving the process of aging to general emotional and physical overall health. Sermorelin peptide cost and availability were impacted, making it important to look for a reliable supplier as it is categorized as a research peptide and has not been strictly regulated ever since.
What are They Known for?
Physical Appearance
Tesamorelin has been speculated to have a great effect on reducing fat excess in the abdominal area. Some users have said that consistent use of Tesamorelin, paired with exercise and a healthy diet, leads to a toned body, positive body image, improved self-esteem, and reduced cardiovascular risks simultaneously.
Lean Muscle Mass
Tesamorelin peptide has been researched as a moderate muscle-building peptide that might stimulate growth hormone (GH) release, and help the body increase lean muscle mass, promoting leaner body structure rather than building muscles. This might be suitable for anyone looking to improve and reshape their body physique.
Fat Loss
Sermorelin was initially used for children with poor growth rates as a peptide naturally occurring in the body and promoting the release of the natural growth hormone. Today, fitness enthusiasts have reported a reduction in body fat and an increase in weight loss, which are some effects this peptide might have on the body.
Metabolic Health
Some studies currently research Tesamorelin peptide and the impact it might have on improving insulin sensitivity, significant diabetes control, and decreased levels of cholesterol.
Bone Health
Some benefits of Tesamorelin and Sermorelin might be related to healthy bone support as increased growth hormone levels impact healthy bone density. This could consequently help the vitality and quality of life, particularly while getting to a certain age when the additional support might be of utmost importance.
Emotional and Cognitive Well-being
One of the suggested benefits of growth hormone-like peptides is the impact on cognitive functions, which is invaluable for reducing the cognitive decline related to aging and maintaining high-functioning cognition.
Mood
Improved mood, reduced symptoms of depression, and enhanced cognitive function have all been reported as one of the benefits of some users facing challenges related to brain fog and fatigue.
Sleep Quality
Sleep enhancement is likely to be one of the Sermorelin’s powers to restore healthy levels of human growth hormone, allowing for deeper, more refreshing sleep. In the modern age, staying asleep and feeling more alert during the day, the effects Sermorelin may offer are invaluable.
Improved Skin Health
Aging is known for causing our body’s collagen levels to drop, leaving our skin thinner and drier. According to some earlier studies, sermorelin helps synthesize collagen, thus restoring skin regeneration and youthfulness.
Anti-Aging
After we reach our 30s, the levels of growth hormones start to decrease. This triggers visible body changes like facial wrinkles and loss of skin elasticity, as well as less visible but equally important ones like fatigue and slower metabolism. Even without sufficient research evidence to support this, Sermorelin has been considered an anti-aging peptide for its probable effect on reversing some visible symptoms of aging, like improving skin elasticity and impacting the overall energy levels, libido, and cardiovascular health.
Body Recovery
One of the standout benefits of tesamorelin and sermorelin might be their potential impact on faster recovery from extensive workouts and bodily injuries, which is of great importance to bodybuilders who face the challenge of prolonged recovery times and muscle soreness after strenuous workouts.
Tesamorelin peptide vs Sermorelin
While both Sermorelin and Tesamorelin peptide are designed to stimulate the production of growth hormone (GH), some of their mechanisms of action are different. Let’s take a closer look at their differences:
On the other hand, Tesamorelin specifically stimulates the production of growth hormones by acting on the hypothalamus, which links the nervous system to the endocrine system via the pituitary gland.
Some studies suggest that Sermorelin may offer additional benefits regarding cardiovascular health by reducing markers of inflammation, potentially leading to a protective effect on the heart.
Tesamorelin peptide appears to have a more direct impact on reducing visceral fat production, which byproduct could be a lower risk of cardiovascular disease.
Some research has speculated that even though Tesamorelin has a half-life of just 30 minutes, its effects on GH can last for up to two weeks. Similar data is not available for Sermorelin.
Safety, usage, dosage
Even though they are considered as well tolerated, as they mimic the action of one of the naturally occurring hormones in the body, Sermorelin and Tesamorelin may cause some of the following:
- injection site reactions (redness and swelling),
- headaches,
- nausea and
- increased blood sugar levels.
Please consider that in many countries, Sermorelin and Tesamorelin are prescription-only medications. They are typically administered via injections, normally subcutaneously (injections under the skin), can be self-administered at home, and are normally injected into the thigh or stomach areas where the body has more fat. The side effects reported are generally mild.
The amount of time it takes to see results after using these peptides can vary depending on several factors, including your physical condition and the dosage used.
Where to buy Tesamorelin and Sermorelin
You can purchase these peptides in our shop, where we guarantee 99% purity. Please note that while buying peptides in the USA, it is crucial to purchase them from reputable suppliers that provide detailed quality specs and purity levels since research peptides do not follow strict medical regulations.
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