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Will Peptides Fail A Drug Test? How Long Are They Detectable?

July 3, 2024
by Peptide Shop
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Before we talk more about peptides showing up on a drug test, we need to make it clear that peptides we’re selling on Peptide.Shop are for lab research only. We do not condone nor encourage the use of peptides without medical supervision or outside of the prescribed therapy.

Back to the topic at hand… in short, depending on the actual test performed, peptides will be detectable anywhere from 1 to 3 months after use so yes, they will fail a drug test. Let’s dig into more details.

The Problem Of Detecting Peptides In A Drug Test

Peptide detection is a bit of a cat and mouse game. Two major problems here are the fact there are so many peptides and that their molecular mass varies so much – from about 2 to 12kDa. 

Why does molecular mass matter? Simply put, we use GC/MS or LC/MS (gas and liquid mass spectrometry) for smaller molecules. And the larger ones undergo bioassay analysis, such as immunoblotting and ELISA.

Since this diversity of drug testing is both time consuming and expensive, they are not usually conducted at once. So, if an individual has been taking a banned substance and undergoes both these tests, they will fail. But, should only one test be performed, the drug test may come out as clean.

A group of scientists from Europe is in the process of trying to solve this exact problem – they are working on a test that would cover all peptides with molecular mass of up to 12kDa. Andreas Thomas and colleagues from the German Sports University Cologne are working on this test that features a combination of immunoaffinity purification with mass spectrometry, applicable to blood and urine.

Both natural and synthetic peptides were subjected to this new test and, though there were some problems with regards to the detection and extraction, it proved promising (when compared with other tests, currently being used to test banned substances in athletes).

Even though the test proved promising, it still requires much refinement and fine tuning before it becomes an official way to test for peptides in athletes (and others).

Peptide Detection Time Frame

When speaking about the peptide test time frame, we have two reference points to help us determine it – urine and hair follicles. 

Urine tests need to be done as soon as possible since they can detect a banned substance 2-3 days after consummation. If performed after this desirable window of opportunity, it will be inconclusive or miss the banned substance completely.

Hair follicles are a different story, as they provide a long term “evidence” of a former drug use (abuse). Hair follicle peptide test can actually show evidence of a substance use 90, or even 100 days before. Good news for us, performing and working on these test, but certainly bad for those looking to abuse them.

Conclusion

Generally speaking, peptides will fail a drug test if done in the appropriate time frame (for urine 2-3 days after, for hair follicles 90-100 after) and with the appropriate test type (depending on the peptide molecular mass). 

There is, of course, still a lot of problems as peptide tests are trying to catch up more and more synthetic peptide products being pushed out into the market, but the testing market is going strong, working on new and improved tests and, though they may not detect a banned substance currently, they certainly will in the future!

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The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease.Peptide Shop is a chemical supplier. Peptide Shop is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic Act. Peptide Shop is not an outsourcing facility as defined under 503D of the Federal Food, Drug, and Cosmetic act. All products are sold for research, laboratory, or analytical purposes only, and are not for human consumption.
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